Simonović lab

Our aim is to determine mechanisms at the structural level that govern the fidelity of gene translation. We are studying: (i) tRNA-dependent synthesis of amino acids, (ii) decoding process, (iii) genetic code reassignment events, (iv) ribonucleoprotein complexes facilitating mRNA translation, and (v) the role of translational machinery in the development of human pathologies. The goal is to expand understanding and knowledge about fundamental biological processes in living organisms.